Pharmacological Modulation of Inflammatory Pathways: Emerging Therapeutic Targets
Keywords:
- Inflammatory Pathways; Pharmacological; Cytokine; chronic diseases
Abstract
Inflammation is a complex biological response crucial for host defence, but when dysregulated, it contributes to chronic diseases such as autoimmune disorders, metabolic syndromes, and cancer. Recent advances in pharmacology have identified novel therapeutic targets within inflammatory pathways, including inflammasomes, cytokine signalling, and epigenetic regulation. This review discusses the latest developments in pharmacological modulation of inflammatory responses, focusing on selective inflammasome inhibitors, cytokine-targeted biologics, and small molecules with anti-inflammatory properties. These emerging therapies hold promise for treating refractory inflammatory diseases with improved efficacy and safety profiles.

